What is Theacrine?
 
Theacrine is an alkaloid structurally similar to Caffeine, and preliminary evidence suggests that it activates similar signalling pathways. The preliminary evidence also suggests less tolerance buildup with theacrine. However, the tolerance effects have not been clinically proven. It is found in the camellia assamica variant, kucha, which is from what Kucha tea is made.
 
One study that noted stimulation with theacrine failed to find any tolerance over the course of seven days; a time frame where caffeine would normally show tolerance. This suggests that the body either does not, or may have a reduced tolerance, to theacrine.
 
TeaCrine is a Natural Caffeine Alternative
 
Based on preclinical and human clinical research, Theacrine benefits include:
Supports healthy metabolic activity and energy production*
Decreases physical discomfort associated with intense exercise*
Reduces perceived exertion from exercise*
Increases cellular protection through oxidation balancing activity*
Supports a positive mood and decreased feelings of stress and irritability*
Increases motivation to exercise and accomplish tasks*
Increases neural drive*
 
Theacrine's Catecholaminergic and Adenosinergic Activity
 
Theacrine’s effects come from the reactions between two neural pathways, catecholaminergic and adenosinergic pathways. By affecting these major pathways and supporting other neurotransmitters, Theacrine increases energy without irritability and enables competitive athletes, active individuals and driven professionals to enhance their physical and mental performance.
 
As documented in an open-source scientific publication on theacrine, concentrated theacrine doses support catecholaminergic signaling. Research on theacrine also indicated that the compound increases activity in the nucleus accumbens (NAc) region of the brain which is believed to support motivation and general cognitive function.
 
In addition to its effects on catecholaminergic signalling, Theacrine (as TeaCrine®) is also thought to regulate adenosinergic activity. Adenosine plays an important role in biochemical processes that promote fatigue, sedation and relaxation. By regulating the activity of the A1 and A2a receptors, Theacrine (as TeaCrine®) may help decrease perceived feelings of fatigue making this a great option for those looking for a theacrine pre workout supplement or other theacrine bodybuilding benefits. It is believed that TeaCrine may be the best theacrine supplement for its ability to promote energy while minimizing chances of irritability. Athletes have reported that Teacrine elevated endurance and strength levels making it the best theacrine supplement for fitness-related uses. Many users have reported that TeaCrine’s dual action on activating catecholamine receptors and regulating adenosinergic receptors helps them maintain healthy levels of focus and energy making it the best theacrine supplement for long bursts of productivity.